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Company Overview

At the heart of cancer care

Racura Oncology (ASX: RAC) is a Phase 3 clinical biopharmaceutical company with a dedicated mission to be at the heart of cancer care.

Racura’s lead asset, RCDS1 (E,E-bisantrene), is a small molecule anticancer agent that primarily functions via G4-DNA & RNA binding, leading to potent inhibition of the important cancer growth regulator MYC. RCDS1 has demonstrated therapeutic activity in cancer patients with a well characterised safety profile. Recent discoveries made by Racura have enabled composition of matter IP filings that provide for 20 years of patent protection over RCDS1.

Racura is advancing a proprietary formulation of RCDS1 (RC220) to address the high unmet needs of patients across multiple oncology indications, with Phase 3 clinical programs in acute myeloid leukaemia (AML), Phase 1a/b program in mutant epidermal growth factor receptor non-small cell lung cancer (EGFRm NSCLC), and a Phase 1a/b program in combination with the anthracycline doxorubicin, where we aim to deliver both cardioprotection and enhanced anticancer activity for solid tumour patients.

Racura Oncology has collaborated with Astex, MD Anderson, Sheba City of Health, UNC School of Medicine, University of Wollongong and University of Newcastle. Racura is actively exploring partnerships, licence agreements or a commercial merger and acquisition to accelerate access to RC220 for patients with cancer across the world. 

Rac About Img

History

2016
Listed on the ASX to bring bisantrene to market as an orphan drug treatment for Acute Myeloid Leukemia (AML)
2021
Discovered bisantrene is not only less cardiotoxic than anthracyclines, but can protect the heart from doxorubicin toxicity while increasing doxorubicin’s anticancer efficacy
2022
Reformulated bisantrene to generate new IP & overcome historical issues with anaphylactoid reactions & peripheral IV administration (RC220)
2024
Advance bisantrene with the aim of demonstrating clinical efficacy in anthracycline cardioprotection, m6A RNA & AML with a commercial focus on pharma partnering & transactions

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